p1 receptor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2247	Swertisin		Adenosine Receptor
	Swertisin, a novel herbal biomolecule, shows a strong antihyperglycemic action. Swertisin is an adenosine A1 receptor antagonist, is known to have antidiabetic, anti-inflammatory and antioxidant effects.		Adenosine Receptor
T22234	Alloxazine		Adenosine Receptor
	Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.		Adenosine Receptor
T7021	ZM241385		Adenosine Receptor
	ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor.		Adenosine Receptor
T1681	Aminophylline	Phyllocontin	PDE , Adenosine Receptor
	Aminophylline (Phyllocontin) is a competitive nonselective phosphodiesterase inhibitor giving a bronchodilatory effect.		PDE , Adenosine Receptor
T16140	MRS 1754		Adenosine Receptor
	MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.		Adenosine Receptor
T8512	BAY-545		Adenosine Receptor
	BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).		Adenosine Receptor
T14078	AB928		Adenosine Receptor
	AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1].		Adenosine Receptor
T12161	N6-Ethyladenosine		Adenosine Receptor
	N6-Ethyladenosine is an adenosine derivative, acts as an agonist of Adenosine receptor(hA1AR and hA3AR with Kis of 4.9 and 4.7 nM , respectively).		Adenosine Receptor
T6979	SCH 58261	SCH58261	Adenosine Receptor
	SCH 58261 is a potent and selective A2a adenosine receptor antagonist.The Ki =2.3 nM for rat A2a and 2 nM is for bovine A2a.		Adenosine Receptor
T8312	Derenofylline		Adenosine Receptor
	Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM)		Adenosine Receptor
T17023	Tecadenoson	CVT-510	Adenosine Receptor
	Tecadenoson (CVT-510) is a selective agonist of A1 adenosine receptor.		Adenosine Receptor
T14944	CGS 15943		PI3K , Adenosine Receptor
	CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively.		PI3K , Adenosine Receptor
T0892	Diphylline	Dyphylline,Diprophylline	PDE , Adenosine Receptor
	Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies...		PDE , Adenosine Receptor
TQ0125	Capadenoson	BAY 68-4986	Adenosine Receptor
	Capadenoson (BAY 68-4986) is a selective adenosine-A1 receptor agonist.		Adenosine Receptor
T14127	Adenosine A1 receptor activator T62		Adenosine Receptor
	Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve...		Adenosine Receptor
T16136	MRS-1706		Adenosine Receptor
	MRS-1706 has Ki values of 1.39, 112, 157, and 230 nM for human A2B, A2A, A1, and A3 receptors respectively. MRS-1706 is an effective and selective adenosine A2B receptor inverse agonist.		Adenosine Receptor
T4290	Preladenant	SCH-420814	Adenosine Receptor
	Preladenant (SCH-420814) is an orally bioavailable antagonist of the adenosine A2A receptor (Ki: 1.1 nM) and has >1000-fold selectivity over all other adenosine receptors.		Adenosine Receptor
T6552	Istradefylline	KW-6002	Adenosine Receptor
	Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Ab...		Adenosine Receptor
T5940	Proxyphylline	7-(2-Hydroxypropyl)theophylline	PDE , Adenosine Receptor
	Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator.		PDE , Adenosine Receptor
T9238	KI-7		Adenosine Receptor
	KI-7 is an adenosine A2B receptor positive allosteric modulator.		Adenosine Receptor